Profile of:

Sofia Ramiro


Sofia Ramiro, MD PhD, is a senior researcher at the Leiden University Medical Center, Leiden, the Netherlands, and a rheumatology consultant at the Zuyderland Medical Center, Heerlen, the Netherlands. Sofia graduated from Nova Medical School in Lisbon, Portugal. She has done a Master in Epidemiology at Maastricht University. She obtained her PhD at the University of Amsterdam on long-term outcomes in ankylosing spondylitis under the supervision of Prof. Landewé and Prof. van der Heijde. She did her training in rheumatology in Leiden and in Heerlen. Her research focuses in axial spondyloarthritis, rheumatoid arthritis, imaging and outcomes research. Sofia Ramiro also has an appointment at Nova Medical School in Lisbon as Visiting Professor. She has been involved in many EULAR task forces for the formulation of recommendations, including being co-convenor on task force updating the recommendations for the management of axSpA. She has authored 200 peer-reviewed manuscripts.

Full name: Sofia Ramiro

Current country: Netherlands

Membership level: Full

Type of membership: EC

Number of publications: 79

Treating spondyloarthritis early: does it matter? Results from a systematic literature review (2023)
https://pubmed.ncbi.nlm.nih.gov/36099043/

Efficacy and safety of non-pharmacological and non-biological interventions: a systematic literature review informing the 2022 update of the ASAS/EULAR recommendations for the management of axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/36261247/

Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/36270657/

ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update (2023)
https://pubmed.ncbi.nlm.nih.gov/36270658/

External validation of the alternative Ankylosing Spondylitis Disease Activity Score in three randomized clinical trials of ixekizumab (2023)
https://pubmed.ncbi.nlm.nih.gov/36282526/

Tapering or discontinuation of biological disease-modifying antirheumatic drugs in axial spondyloarthritis: A review of the literature and discussion on current practice (2023)
https://pubmed.ncbi.nlm.nih.gov/36336291/

Hounsfield Units measured in low dose CT reliably assess vertebral trabecular bone density changes over two years in axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/36521287/

Social Media Use Among Members of the Assessment of Spondyloarthritis International Society: Results of a Web-Based Survey (2023)
https://pubmed.ncbi.nlm.nih.gov/36626201/

Translation and cross-cultural adaptation of coping with rheumatic stressors instrument into Turkish language (2023)
https://pubmed.ncbi.nlm.nih.gov/36695311/

Inflammation, bone loss and 2-year bone formation at the same vertebra in axial spondyloarthritis: a multilevel MRI and low-dose CT analysis (2023)
https://pubmed.ncbi.nlm.nih.gov/36759008/

Coping with rheumatic stressors (CORS) questionnaire: Spanish translation and cross-cultural adaptation (2023)
https://pubmed.ncbi.nlm.nih.gov/36781514/

Good construct validity of the CT Syndesmophyte Score (CTSS) in patients with radiographic axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/36914212/

Bone marrow edema in the sacroiliac joints is associated with the development of structural lesions at the same anatomical location over time in patients with axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/37263068/

ASAS consensus definition of early axial spondyloarthritis (2023)
https://pubmed.ncbi.nlm.nih.gov/37321799/

Looking through the window of opportunity in axial spondyloarthritis? (2023)
https://pubmed.ncbi.nlm.nih.gov/37355203/

Do fatty lesions explain the effect of inflammation on new syndesmophytes in patients with radiographic axial spondyloarthritis? Results from the SIAS cohort and ASSERT trial (2023)
https://pubmed.ncbi.nlm.nih.gov/37407237/

Effectiveness of biosimilar infliximab CT-P13 compared to originator infliximab in biological-naïve patients with rheumatoid arthritis and axial spondyloarthritis: data from the Portuguese Register (2023)
https://pubmed.ncbi.nlm.nih.gov/37421191/

How is early spondyloarthritis defined in the literature? Results from a systematic review (2022)
https://pubmed.ncbi.nlm.nih.gov/35667332/

Instrument selection for the ASAS core outcome set for axial spondyloarthritis (2022)
https://pubmed.ncbi.nlm.nih.gov/35680390/

Low-dose CT hounsfield units: a reliable methodology for assessing vertebral bone density in radiographic axial spondyloarthritis (2022)
https://pubmed.ncbi.nlm.nih.gov/35732346/

Muscle dysfunction in axial spondylarthritis: the MyoSpA study. (2022)
https://pubmed.ncbi.nlm.nih.gov/34874829/

Role of vertebral corner inflammation and fat deposition on MRI on syndesmophyte development detected on whole spine low-dose CT scan in radiographic axial spondyloarthritis (2022)
https://pubmed.ncbi.nlm.nih.gov/35803614/

Safety and Efficacy of Bimekizumab in Patients With Active Ankylosing Spondylitis: Three-Year Results From a Phase IIb Randomized Controlled Trial and Its Open-Label Extension Study (2022)
https://pubmed.ncbi.nlm.nih.gov/35829672/

A randomized, double-blind, placebo-controlled 12-week trial of infliximab in patients with juvenile-onset spondyloarthritis (2022)
https://pubmed.ncbi.nlm.nih.gov/35941676/

Does gender influence outcome measures similarly in patients with spondyloarthritis? Results from the ASAS-perSpA study (2022)
https://pubmed.ncbi.nlm.nih.gov/36096523/

Development and validation of an alternative ankylosing spondylitis disease activity score when patient global assessment is unavailable (2021)
https://pubmed.ncbi.nlm.nih.gov/32572483/

Determinants of the patient global assessment of well-being in early axial spondyloarthritis: 5-year longitudinal data from the DESIR cohort (2021)
https://pubmed.ncbi.nlm.nih.gov/32766697/

Tumor Necrosis Factor Inhibitors Reduce Spinal Radiographic Progression in Patients With Radiographic Axial Spondyloarthritis: A Longitudinal Analysis From the Alberta Prospective Cohort (2021)
https://pubmed.ncbi.nlm.nih.gov/33538097/

Peripheral arthritis and higher disease activity lead to more functional impairment in axial spondyloarthritis: Longitudinal analysis from ESPAXIA (2021)
https://pubmed.ncbi.nlm.nih.gov/33901989/

Association between individual and country-level socioeconomic factors and work participation in spondyloarthritis including psoriatic arthritis: Analysis of the ASAS-perSpA study (2021)
https://pubmed.ncbi.nlm.nih.gov/34153894/

Sick leave in early axial spondyloarthritis: the role of clinical and socioeconomic factors. Five-year data from the DESIR cohort (2021)
https://pubmed.ncbi.nlm.nih.gov/34172511/

Lumbar myofascial physical properties in healthy adults: myotonometry vs. shear wave elastography measurements (2021)
https://pubmed.ncbi.nlm.nih.gov/34226434/

Biological DMARDs and disease modification in axial spondyloarthritis: a review through the lens of causal inference (2021)
https://pubmed.ncbi.nlm.nih.gov/34253683/

How do clinical and socioeconomic factors impact on work disability in early axial spondyloarthritis? Five-year data from the DESIR cohort (2021)
https://pubmed.ncbi.nlm.nih.gov/34320627/

Individual and country-level socioeconomic factors and health outcomes in spondyloarthritis: analysis of the ASAS perSpA study (2021)
https://pubmed.ncbi.nlm.nih.gov/34387300/

Individual and country-level socioeconomic factors and health outcomes in spondyloarthritis: analysis of the ASAS perSpA study (2021)
https://pubmed.ncbi.nlm.nih.gov/34387300/

The ASAS-OMERACT core domain set for axial spondyloarthritis (2021)
https://pubmed.ncbi.nlm.nih.gov/34489113/

Muscle dysfunction in axial spondylarthritis: the MyoSpA study (2021)
https://pubmed.ncbi.nlm.nih.gov/34874829/

The role of muscle in the susceptibility and progression of axial Spondyloarthritis: The MyoSpA Study Protocol (2021)
https://pubmed.ncbi.nlm.nih.gov/34962249/

The role of muscle in the susceptibility and progression of axial Spondyloarthritis: The MyoSpA Study Protocol (2021)
https://pubmed.ncbi.nlm.nih.gov/34962249/

Determinants of the physician global assessment of disease activity and influence of contextual factors in early axial spondyloarthritis (2020)
https://pubmed.ncbi.nlm.nih.gov/32986932/

Which imaging outcomes for axSpA are most sensitive to change? A 5-Year analysis of The DESIR Cohort (2020)
https://pubmed.ncbi.nlm.nih.gov/32976683/

Do Smoking and Socioeconomic Factors Influence Imaging Outcomes in Axial Spondyloarthritis? Five-Year Data From the DESIR Cohort. (2020)
https://pubmed.ncbi.nlm.nih.gov/32562362/

No relationship between bone mineral density and syndesmophyte formation at the same level in the lumbar spine of patients with radiographic axial Spondyloarthritis (2020)
https://pubmed.ncbi.nlm.nih.gov/33310864/

Inflammation of the sacroiliac joints and spine on MRI predicts structural changes on MRI in axial spondyloarthritis: 5-year data from DESIR (2020)
https://pubmed.ncbi.nlm.nih.gov/32937029/

Performance and Predictors of Minimal Disease Activity Response in Peripheral Spondyloarthritis Patients Treated With Adalimumab (2020)
https://pubmed.ncbi.nlm.nih.gov/32937016/

Disease activity is associated with spinal radiographic progression in axial spondyloarthritis independently of exposure to tumour necrosis factor inhibitors (2020)
https://pubmed.ncbi.nlm.nih.gov/33118014/

What is axial spondyloarthritis? A latent class and transition analysis in the SPACE and DESIR cohorts (2020)
https://pubmed.ncbi.nlm.nih.gov/31980546/

Eligibility criteria for biologic disease-modifying antirheumatic drugs in axial spondyloarthritis: going beyond BASDAI (2020)
https://pubmed.ncbi.nlm.nih.gov/32144137/

Integrated longitudinal analysis does not compromise precision and reduces bias in the study of imaging outcomes: A comparative 5-year analysis in the DESIR cohort (2020)
https://pubmed.ncbi.nlm.nih.gov/32209237/

The European Portuguese version of the ASAS Health Index for Patients with Spondyloarthritis: Measurement properties (2020)
https://pubmed.ncbi.nlm.nih.gov/32572012/

Work Disability in Axial Spondyloarthritis (2020)
https://pubmed.ncbi.nlm.nih.gov/32719993/

Effectiveness of switching between TNF inhibitors in patients with axial spondyloarthritis: is the reason to switch relevant? (2020)
https://pubmed.ncbi.nlm.nih.gov/32825839/

Imaging Outcomes for Axial Spondyloarthritis and Sensitivity to Change: A Five-Year Analysis of the DESIR Cohort (2020)
https://pubmed.ncbi.nlm.nih.gov/32976683/

Determinants of the Physician Global Assessment of Disease Activity and Influence of Contextual Factors in Early Axial Spondyloarthritis (2020)
https://pubmed.ncbi.nlm.nih.gov/32986932/

Which disease activity outcome measure discriminates best in axial spondyloarthritis? A systematic literature review and meta-analysis (2020)
https://pubmed.ncbi.nlm.nih.gov/33085754/

Characteristics and burden of disease in patients with radiographic and non-radiographic axial Spondyloarthritis: a comparison by systematic literature review and meta-analysis. (2019)
https://pubmed.ncbi.nlm.nih.gov/31803500/

Do patients with axial spondyloarthritis with radiographic sacroiliitis fulfil both the modified New York criteria and the ASAS axial spondyloarthritis criteria? Results from eight cohorts (2019)
https://pubmed.ncbi.nlm.nih.gov/31362994/

Is it Useful to Repeat Magnetic Resonance Imaging of the Sacroiliac Joints After Three Months or One Year in the Diagnosis of Patients With Chronic Back Pain and Suspected Axial Spondyloarthritis? (2019)
https://pubmed.ncbi.nlm.nih.gov/30203929/

Spinal Radiographic Progression in Early Axial Spondyloarthritis: Five-Year Results From the DESIR Cohort (2019)
https://pubmed.ncbi.nlm.nih.gov/30354022/

Is active sacroiliitis on MRI associated with radiographic damage in axial spondyloarthritis? Real-life data from the ASAS and DESIR cohorts (2019)
https://pubmed.ncbi.nlm.nih.gov/30544144/

Performance of referral strategies for spondyloarthritis: a population-based nationwide study (2019)
https://pubmed.ncbi.nlm.nih.gov/30649551/

Individual-level and country-level socioeconomic determinants of disease outcomes in SpA: multinational, cross-sectional study (ASAS-COMOSPA) (2019)
https://pubmed.ncbi.nlm.nih.gov/30674477/

Measuring spinal mobility in early axial spondyloarthritis: does it matter? (2019)
https://pubmed.ncbi.nlm.nih.gov/30879078/

Characteristics and burden of disease in patients with radiographic and non-radiographic axial Spondyloarthritis: a comparison by systematic literature review and meta-analysis (2019)
https://pubmed.ncbi.nlm.nih.gov/31803500/

5-year follow-up of spinal and sacroiliac MRI abnormalities in early axial spondyloarthritis: data from the DESIR cohort (2019)
https://pubmed.ncbi.nlm.nih.gov/32396521/

Sick leave and its predictors in ankylosing spondylitis: long-term results from the Outcome in Ankylosing Spondylitis International Study. (2018)
https://pubmed.ncbi.nlm.nih.gov/30564453/

Frequency of Impaired Spinal Mobility in Patients with Chronic Back Pain Compared to Patients with Early Axial Spondyloarthritis (2018)
https://pubmed.ncbi.nlm.nih.gov/29961689/

Low-dose CT detects more progression of bone formation in comparison to conventional radiography in patients with ankylosing spondylitis: results from the SIAS cohort (2018)
https://pubmed.ncbi.nlm.nih.gov/29127092/

Development of the CT Syndesmophyte Score (CTSS) in patients with ankylosing spondylitis: data from the SIAS cohort (2018)
https://pubmed.ncbi.nlm.nih.gov/29127093/

Inequity in biological DMARD prescription for spondyloarthritis across the globe: results from the ASAS-COMOSPA study (2018)
https://pubmed.ncbi.nlm.nih.gov/29222349/

Is radiographic progression in radiographic axial spondyloarthritis related to matrix metalloproteinase degradation of extracellular matrix? (2018)
https://pubmed.ncbi.nlm.nih.gov/29765702/

Work participation in spondyloarthritis across countries: analysis from the ASAS-COMOSPA study (2018)
https://pubmed.ncbi.nlm.nih.gov/29860232/

Which scoring method depicts spinal radiographic damage in early axial spondyloarthritis best? Five-year results from the DESIR cohort (2018)
https://pubmed.ncbi.nlm.nih.gov/30053219/

Are gender-specific approaches needed in diagnosing early axial spondyloarthritis? Data from the SPondyloArthritis Caught Early cohort (2018)
https://pubmed.ncbi.nlm.nih.gov/30285842/

Uncovering the heterogeneity of disease impact in axial spondyloarthritis: bivariate trajectories of disease activity and quality of life (2018)
https://pubmed.ncbi.nlm.nih.gov/30487997/

Cardiovascular morbidity and mortality in ankylosing spondylitis and psoriatic arthritis (2018)
https://pubmed.ncbi.nlm.nih.gov/31171309/

Translation and cross-cultural adaptation of the ASAS Health Index and ASAS Environmental Factors Item Set into European Portuguese Language (2017)
https://pubmed.ncbi.nlm.nih.gov/28860446/

Association of Comorbidities in Spondyloarthritis With Poor Function, Work Disability, and Quality of Life: Results From the Assessment of SpondyloArthritis International Society Comorbidities in Spondyloarthritis Study. (2017)
https://pubmed.ncbi.nlm.nih.gov/29125900/