Profile of:

Rafaël Valle Oñate

Dr. Rafael Valle-Oñate made his medical studies of Internal Medicine/ Immunology and Rheumatology in Colombian National and Rosario Universities, and made his Scholar Postdoctoral Research Fellow in Rheumatology and Immunology during 3 years at Brigham’s and Women’s Hospital affiliate of Harvard University, under Dr. Peter Schur. Director and Founder of the Colombian Clinic of Rheumatology, Salud Reinun, he has treated and educated more than 30,000 patients, most of them within a social service program around the country. He also founded the Department of Rheumatology and Immunology of the Colombian Military Hospital at Bogotá, creating a post-graduate program in Rheumatology, where more than 50 physicians have obtained their title in rheumatology and more than 500 fellows of different specialties have done partial training. He has reached leadership positions in scientific groups such Panlar, where he was the Director of the SpA and PsA Study Groups, and has contributed to the institutional empowerment for more than 30 years. He was also a member of the Steering Committee of GRAPPA, President of Colombian Association of Rheumatology and founder editor of its Journal, and founder of the ACCA association. Additionally, he has actively participated in groups such as IGAS, Spartan, and Gladar. Dr. Valle-Oñate has more than 50 peer-reviewed original articles including the identification of a gene different from HLA-B27 associated to undifferentiated SpA (1997) which 20 years later was classified as gene HLA-B15 associated to peripheral SpA. Moreover, Dr. Valle-Oñate is the co-editor of the first Spanish language book regarding SpA (2007), and organized the First Pan-American Congress in SpA in Latin America (2005). Throughout his life, he has received different recognitions as Master of the American College of Rheumatology (ACR ), the Medicine National Prize, and PANLAR Master and Innovation Awards. He was elected to ASAS in 2004. In the present, Dr Valle-Oñate is interested and enthusiastic about the field of Precision Medicine in Rheumatology.

Full name: Rafaël Valle Oñate

Current country: Colombia

Membership level: Full

Type of membership: Member

Number of publications: 28

Assessment of SpondyloArthritis International Society (ASAS) Consensus on Spanish Nomenclature for Spondyloarthritis. (2020)

Treatment of uveitis and ankylosing spondylitis refractory to three tumor necrosis factor alpha inhibitors drugs with golimumab. (2020)

The Frequency of HLA-B27 in a Colombian Population with Signs of Spondyloarthritis (2018)

Validation and reliability of translation of the ASAS Health Index in a Colombian Spanish-speaking population with spondyloarthritis (2018)

Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitis (2018)

Prevalence of Comorbidities and Risk Factors for Comorbidities in Patients with Spondyloarthritis in Latin America: A Comparative Study with the General Population and Data from the ASAS-COMOSPA Study (2018)

Is there a relationship between spondyloarthritis and periodontitis? A case-control study (2017)

Genetic diagnostic profiling in axial spondyloarthritis: a real world study (2017)

Factors associated with the decision of the rheumatologist to order sacroiliac joints magnetic resonance imaging (SI-MRI) or HLA-B27 testing in the diagnostic work-up of patients with spondyloarthritis in clinical practice (2017)

Higher Levels of Secretory IgA Are Associated with Low Disease Activity Index in Patients with Reactive Arthritis and Undifferentiated Spondyloarthritis (2017)

Gastrointestinal Symptoms and Elevated Levels of Anti- Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritis (2017)

Analysis and performance of various classification criteria sets in a Colombian cohort of patients with spondyloarthritis (2016)

ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients (2015)

Analysis of HLA-B15 and HLA-B27 in spondyloarthritis with peripheral and axial clinical patterns (2015)

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1 (2015)

Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis (2015)

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci (2013)

Association of tumor necrosis factor alpha-308 promoter polymorphism with spondyloarthritides patients in Colombia (2012)

Psoriasis and psoriatic arthritis in Peruvian aborigines: a report from the GRAPPA 2011 annual meeting (2012)

Global partnering opportunities and challenges of psoriasis and psoriatic arthritis in Latin America: a report from the GRAPPA 2010 annual meeting (2012)

The association between serum levels of potential biomarkers with the presence of factors related to the clinical activity and poor prognosis in spondyloarthritis (2012)

The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general (2011)

Epidemiology of spondyloarthritis in Colombia (2011)

Psoriatic arthritis in South and Central America (2011)

Association between Th-17 cytokine profile and clinical features in patients with spondyloarthritis (2011)

The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection (2009)

Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis (2008)

Panamerican Congress of Spondyloarthropathies, Cartagena, Columbia, October 20-22, 2005: Latin American rheumatology comes of age! (2006)