Profile of:

Deepak Jadon

I am a consultant rheumatologist, Director of the Rheumatology Research Unit, lead for psoriatic arthritis (PsA) and co-lead for axSpA at Cambridge University Hospitals. Having grown up in Cardiff, I graduated from the University of Wales College of Medicine in 2003, and then undertook clinical training in rheumatology and general internal medicine in Bath and Bristol between 2007 - 2015. I completed my PhD thesis on ‘biomarkers of psoriatic arthritis phenotypes’ at the Royal National Hospital for Rheumatic Diseases (Bath, UK) in 2015. I have particular expertise in the investigation and management of psoriatic arthritis (PsA), ankylosing spondylitis (AS), spondyloarthritis (SpA) and rheumatoid arthritis (RA). I am qualified in the use of musculoskeletal ultrasound to improve diagnostic accuracy and assessment of disease activity. My research interests include genetic and serum biomarkers of PsA, AS and SpA, in particular those that predict prognosis and developing psoriatic spondyloarthritis or arthritis mutilans. I have researched the clinical and radiographic differences between PsA and AS, and juvenile- vs. adult-onset AS. As Director of the Rheumatology Research Unit, I lead on >10 phase 2a – 4 clinical studies of novel therapeutic agents for PsA, AS and RA. The research unit currently has >20 active clinical trials including in addition SLE, Sjogren's, GCA, PMR, gout, and chronic pain. I have particular expertise in existing and emerging biologics (biologicals such TNFi, IL-17i, IL-23i, JAKi, PDE4i) and biosimilars therapies, both in clinical practice and clinical trials. As an Associate-PI at the University of Cambridge, my research interests include biomarkers (genetic, serum, cellular, MRI, ultrasound and radiographic) of psoriatic arthritis and ankylosing spondylitis; in terms of disease severity, phenotype and treatment response. In October 2020, I was appointed Director of Studies At Emmanuel College, University of Cambridge.

Full name: Deepak Jadon

Current country: United Kingdom

Membership level: Full

Type of membership: Member

Number of publications: 29

Multidisciplinary working in the management of axial and peripheral spondyloarthritis (2020)

Depression in patients with spondyloarthritis: prevalence, incidence, risk factors, mechanisms and management (2020)

Treatment of psoriatic arthritis with biologic and targeted synthetic DMARDs: British Society for Rheumatology guideline scope (2020)

Applying precision medicine to unmet clinical needs in psoriatic disease (2020)

Proceedings of the 2019 GRAPPA Collaborative Research Network Meeting (2020)

Human osteoarthritic synovial fluid increases excitability of mouse dorsal root ganglion sensory neurons: an in-vitro translational model to study arthritic pain (2020)

Proceedings of the 2018 GRAPPA Collaborative Research Network Meeting (2019)

Psoriatic Nail Dystrophy Is Associated with Erosive Disease in the Distal Interphalangeal Joints in Psoriatic Arthritis: A Retrospective Cohort Study (2019)

Trajectory of radiographic change over a decade: the effect of transition from conventional synthetic disease-modifying antirheumatic drugs to anti-tumour necrosis factor in patients with psoriatic arthritis (2019)

Protocol for the insight study: a randomised controlled trial of single-dose tocilizumab in patients with depression and low-grade inflammation (2018)

Proceedings of the 2017 GRAPPA Collaborative Research Network Meeting (2018)

The Benefits and Challenges of Setting Up a Longitudinal Psoriatic Arthritis Database (2018)

Prevalence and predictors of tumour necrosis factor inhibitor persistence in psoriatic arthritis (2018)

Th17 cell responses in spondyloarthritis (2017)

Serum bone-turnover biomarkers are associated with the occurrence of peripheral and axial arthritis in psoriatic disease: a prospective cross-sectional comparative study (2017)

A rare coding allele in IFIH1 is protective for psoriatic arthritis (2017)

Proceedings of the GRAPPA 2016 Retreat (2017)

Axial Disease in Psoriatic Arthritis study: defining the clinical and radiographic phenotype of psoriatic spondyloarthritis (2017)

Implications of the diversity of class I HLA associations in psoriatic arthritis (2016)

Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis: A Proof-of-concept Study (2016)

Psoriatic Arthritis Mutilans: Characteristics and Natural Radiographic History (2015)

Serum soluble bone turnover biomarkers in psoriatic arthritis and psoriatic spondyloarthropathy (2015)

Clinical outcomes and progression to orthopedic surgery in juvenile- versus adult-onset ankylosing spondylitis (2015)

Feasibility, reliability, and sensitivity to change of four radiographic scoring methods in patients with psoriatic arthritis (2014)

Juvenile versus adult-onset ankylosing spondylitis — clinical, radiographic, and social outcomes. a systematic review (2013)

Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis (2013)

Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis (2013)

The ClASsification for Psoriatic ARthritis (CASPAR) criteria–a retrospective feasibility, sensitivity, and specificity study (2012)

Long-term remission following withdrawal of dopamine agonist therapy in subjects with microprolactinomas (2005)