Profile of:

Muhammad Asim Khan


Dr. Muhammad Asim Khan obtained his medical degree in 1965, and after 2 years of Army Service, he obtained his postgraduate training in the UK and the US. He completed his rheumatology fellowship in Cleveland, OH in 1973 and joined the faculty of Case Western Reserve University in that city. He served there till 2012 as a tenured full Professor of Medicine when he was awarded the title of Professor Emeritus of Medicine. Three years later he was inducted into the Medical Hall of Honor at MetroHealth Medical Center, the hospital he has served since 1971. He has been elected as a Master of both the American College of Physicians (ACP) and the American College of Rheumatology (ACR), and a Fellow of the Royal College of Physicians of UK (FRCP). He is a recipient of the ACR’s Distinguished Rheumatologist Award and the Ohio Association of Rheumatology's Lifetime Achievement Award. He had served as a member of the National Advisory Board for the National Institute of Arthritis and Musculoskeletal and Skin Disorders (NIAMS). His research interests center around the clinical, immunogenetic and therapeutic aspects of rheumatic diseases, with special focus on ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA). He has published 3 books and edited 4 others, and has authored >50 book chapters and >245 journal articles, in addition to >185 scientific abstracts and letters to editor. He is the Section Editor for SpA for the journal Curr Rheumatol Rep since 2006, after having served in the same role from 1993 to 2001 for Curr Opin Rheumatol. He is a peer reviewer for UpToDate, and has served as an editorial board member or a reviewer for several journals. He is one of the founding members of ASAS, SPARTAN, and GRAPPA, and a recipient of SPARTAN's Lifetime Achievement Award. He has served on various advisory committees in these organizations, as well as the ACR, ACP, and the Spondylitis Association of America (SAA). He has been suffering from severe AS since age 12, and was bestowed an award from the SAA for a "lifetime of dedication and devotion to people with spondylitis" and also their Greg Field Award that is given to "individuals with AS who have persevered and gone on to be of service to others”.

Full name: Muhammad Asim Khan

Current country: United States

Membership level: Full

Type of membership: Honorary

Number of publications: 21

Ermann J, Deodhar A, Khan MA, Weisman MH, Reveille J. Twenty years of SPARTAN: from inception to impact (SPARTAN 2023 Annual Meeting Proceedings). Curr Rheumatol Rep. 2024;26:96-101. doi.org/10.1007/s11926-023-01131-8. (2024)
https://www.ncbi.nih.gov/

Khan MA. HLA-B*27 and ankylosing spondylitis: 50 years of insight and discovery. Curr Rheumatol Rep. 2023;25:327-340. doi: 10.1007/s11926-023-01118-5. (2023)
https://www.ncbi.nih.gov/

Khan MA, Yong Su-Boon, Wei J. Ankylosing spondylitis: History, epidemiology, and HLA-B27. Editorial. Intl J Rheum Dis. 2023 Mar;26(3):413-414. doi: 10.1111/1756-185X.14547. PMID: 36859756. (2023)
https://www.ncbi.nih.gov/

Khan MA, Yong Su-Boon, van der Linden S. The Challenge of New Classification Criteria for Axial Spondyloarthritis. Editorial. Intl J Rheum Dis. 2023 Jul;26(7):1225-1226. doi: 10.1111/1756-185X.14685. PMID: 37394892. doi: 10.1111/1756-185X.14685 (2023)
https://www.ncbi.nih.gov/

Bittar M, Khan MA, Magrey M. Overdiagnosis, underdiagnosis, and misdiagnosis of axial spondyloarthritis. Curr Rheumatol Rep. 2023; 25, 47–55 https://doi.org/10.1007/s11926-022-01096-0 (2023)
https://www.ncbi.nih.gov/

Magrey MN, Walsh JA, Flierl S, Howard RA, Calheiros RC, Wei D, Khan MA. The International Map of Axial Spondyloarthritis (IMAS): a US patient perspective on diagnosis and burden of disease. ACR Open Rheumatology. 2023 April, DOI 10.1002/acr2.11543 (2023)
https://www.ncbi.nih.gov/

Chaudhary H, López-Medina C, Khan MA, Dougados M, Magrey MN. Clinical Profile and Treatment Utilization based on HLA-B*27 status in Axial Spondyloarthritis: Results from ASAS-PerSpA Study. RMD Open 2023 Jul;9(3):e003179. doi: 10.1136/rmdopen-2023-003179. (2023)
https://www.ncbi.nih.gov/

Yousif P, Nahra V, Khan MA, Magrey M. Axial Psoriatic Arthritis — Clinical Characteristics and Treatment Controversies. Is Axial Psoriatic Arthritis Different from Ankylosing Spondylitis? Bone Joint Spine July 24, 2023. doi: 10.1016/j.jbspin.2023.105625. (2023)
https://www.ncbi.nih.gov/

Kiefer D, Baraliakos X, Khan MA. Diffuse idiopathic skeletal hyperostosis and axial spondyloarthritis: similarities and differences. Exploration of Musculoskeletal Diseases (Explor Musculoskeletal Dis). 2023; 1:194–206. doi: 10.37349/emd. 2023.00022. (2023)
https://www.ncbi.nih.gov/

van der Linden S, Khan MA, Li Z, Baumberger H, Zandwijk HV, Khan K, Villiger P, Brown MA. Factors predicting axial spondlyoarthritis among first-degree relatives of probands with ankylosing spondylitis. A family study spanning 35 years. Ann Rheum Dis. 2022; 81(6):831-7. doi: 10.1136/annrheumdis-2021-222083 (2022)
https://pubmed.ncbi.nlm.nih.gov/

Li Z, van der Linden S, Khan MA, Baumberger H, Zandwijk HV, Khan MK, Villiger P, Brown MA. Heterogeneity of Axial Spondyloarthritis – Genetics, Sex and Structural Damage Matter. RMD Open. 2022;8:e002302. doi:10.1136/ rmdopen-2022-002302 (2022)
https://pubmed.ncbi.nlm.nih.gov/

van der Linden S, Khan MA, Baumberger H, Li Z, Zandwijk HV, Khan MK, Villiger P, Brown MA. Recurrence of Axial Spondyloarthritis among First-Degree Relatives in a Prospective 35-year-follow-up Family Study. RMD Open. 2022;8:e002208. doi:10.1136/ rmdopen-2022-002208 (2022)
https://pubmed.ncbi.nlm.nih.gov/

Couto AR, Parreira B, Power DM, Pinheiro L, Dias JM, Novofastovski I, Eshed I, Sarzi-Puttini P, Pappone N, Atzeni F, Verlaan JJ, Kuperus J, Bieber A, Ambrosino P, Kiefer D, Khan MA, Mader R, Baraliakos X and Armas JB. Evidence for a genetic contribution to the ossification of spinal ligaments in Ossification of Posterior Longitudinal Ligament and Diffuse idiopathic skeletal hyperostosis: A narrative review. Frontier Genetics. 13:987867. doi: 10.3389/fgene.2022.987867 (2022)
https://pubmed.ncbi.nlm.nih.gov/

Robinson PC, van der Linden S, Khan MA, Taylor WJ. Axial Spondyloarthritis: Concept, construct, classification and implications for therapy. Nat Rev Rheumatol. 2021 Feb(2);17(2):109-118 (2021)
https://pubmed.ncbi.nlm.nih.gov

Mader R, Pappone N, Baraliakos X,……… Khan MA. Diffuse Idiopathic Skeletal Hyperostosis (DISH) and a Possible Inflammatory Component. Curr Rheumatol Rep. 23, 6 (2021). doi: 10.1007/s11926-020-00972-x (2021)
https://pubmed.ncbi.nlm.nih.gov/

Akkoc N, Khan MA. JAK inhibitors for axial spondyloarthritis: What does the future hold? Curr Rheumatol Rep. 23, 34 (2021). doi: 10.1007/s11926-021-01001-1 (2021)
https://pubmed.ncbi.nlm.nih.gov/

Klitz U, Boonen A, van der Heijde D, ,…. Khan MA, …. Braun J. Developmentof important contextual item set relevant to global functioning and health in patients with axial spondyloarthritis – the Environmental Factor Item Set accompanying the ASAS Health Index. Rheumatology. doi: 10.1093/rheumatology/keab653 (2021)
https://pubmed.ncbi.nlm.nih.gov/

Bittar M, Yong WC, Magrey M, Khan MA. Worldwide Differences in Clinical Phenotype of Axial Spondyloarthritis. Curr Rheumatol Rep. 23, 76 (2021). doi: 10.1007/s11926-021-01043-5 (2021)
https://pubmed.ncbi.nlm.nih.gov/

Chetrit M, Kapadia S. Khan MA. State of the art management of aortic valve disease in ankylosing spondylitis. Curr Rheumatol Rep. 2020 May 14;22(6):23. (2020)
https://www.ncbi.nih.gov

Akkoc N, Khan MA. Is axial spondyloarthritis more common than rheumatoid arthritis? Curr Rheumatol Rep. 22, 54 (2020). doi: 10.1007/s11926-020-00934-3 (2020)
https://www.ncbi.nih.gov/

Magrey M, Charles T, Khan MA. Relationship between disease activity measures, functional status, and fibromyalgia symptom scale in ankylosing spondylitis: a cross-sectional study. J Clin Rheumatol. July 22, 2020. doi: 10.1097/RHU.0000000000001490 (2020)
https://www.ncbi.nih.gov/